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New data scientists from the Research Institute of Scripps in California, USA, said that the antiepileptic drug gabapentin affects certain components of the mechanism of alcohol creatine dependence, thereby supporting the suggestion that he could become one of the drugs for the treatment creatine of alcoholism, reports Science Daily. The study showed that gabapentin normalizes the function of certain brain cells that have been modified under the influence of chronic alcohol abuse. creatine These cells are found in brain regions creatine known as the central amygdala, which plays an important role in the behavior under stress and monitoring alcohol consumption. I participated in a study of rodents after gabapentin reduced the need for alcohol. Previous studies have shown that gabapentin is effective in reducing alcohol consumption and reduces the symptoms of alcohol withdrawal syndrome, reducing the craving for alcohol. However, the question of exactly how the drug works, while remained unclear. At the cellular level, alcohol dependence is associated with an increase in the coupling creatine strength between the nerve cells in the central amygdala. Gabapentin was found to reduce the strength of this connection and normalizes the function of neurons. The scientists plan to further investigate the mechanism of action of gabapentin on brain cells. In addition, currently in clinical trials of efficacy as a cure for alcoholism. The research is supported by the National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Institutes of Health USA (NIH) Research and Harold Dorris Neurological Institute. Source: Pohmelya.NET
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