But, having looked it up, I can tell you that codeine/acetaminophen and even codeine alone has over

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I had dental surgery last Thursday and as fun as that was, managing the pain since has been ever more so. It got me to thinking that mixing bipolar and codeine likely isn t the best idea. What Is Codeine?
Codeine is an opioid medication and can naturally be derived from opium and a form of morphine. It is primarily used as a pain medication but can be used for a myriad of other things mitosis such as suppressing preterm labor contractions and is on the list of essential medications as assessed by the World Health Organization.
I will be the first one to say that I didn t check the interaction list or seriously question anyone before taking this stuff. This was my bad but, in my defense, mitosis it s sort of something that healthcare professionals should have been asking me about (I.e., What other medications are you taking?). But they didn t. And when I went to pick up the prescription I was on sedative medication so it certainly didn t occur to me to mount a major query offensive (walking was challenging at that point).
But, having looked it up, I can tell you that codeine/acetaminophen and even codeine alone has over 200 significant interactions mitosis and many serious (use alternative) interactions. And yes, some of these are codeine and bipolar/psych med interactions.
I ve looked through the list and many of the significant interactions mitosis are either an increase in sedating effects (most antipsychotics and benzodiazepines, some antidepressants) or an increasing mitosis of potency (several antidepressants) both of which require mitosis close monitoring (according to Medscape). Here s a sampling: Bupropion (Wellbutrin) increases level of effect of codeine by effecting hepatic enzyme CYP206 metabolism. Significant interaction possible. Desvenlafaxine (Pristiq) inhibits CYP206, with higher desvenlafaxine dosages (i.e., 400 mg) decrease the CYP206 substrate dose by up to 50%, no dosage adjustment needed with desvenlafxine dosages < 100 mg. Quetiapine (Seroquel) both increase sedation. Potential for interaction, monitor.
(As an interesting side note, the opioid oxycodone has also been known to cause mania in bipolar individuals and has also been tried as an adjunctive treatment in bipolar depression .) Bipolar and Codeine
All of this is to say that it s not very fun for me to be on yet another medication in conjunction with all the psychiatric medications I currently take. It feels rather like all the meds have gotten together to throw a kegger in my brain. I d avoid the experience again, if I could.
And, mitosis of course, I should have done this research and discussed it with my doctor long before going on the medication. This isn t always possible, of course, but it was in my case and I should have done it. Feel free to learn from my error here and do your due diligence.
(It s also worth noting that not all interactions are going to be known and that we, as a bipolar population, are special and our reactions may simply be unusual. That s why closely monitoring your bipolar symptoms and psychiatric wellbeing in general while going on any medication mitosis prescription or over-the-counter is critical.)
Since getting over yet another cold during this terrible cold & flu season I’ve found there’s nasty interactions with some of these cold and cough medications as well. It’s worth checking out with a pharmacist before using. For instance with Benedryl I suffered severe sedation. Even with Cold FX I had terrible vertigo. I never had these type of problems before being on bipolar medication
Don’t forget Dextromorphan, I had the joy of discovering what that was like with Wellbutrin several months ago. I had a really bad cough and for two days I was trying to figure out why my eyes we