Gabapentin (Gabapentine) | Blog students - medic
Synonyms: Gabagamma, Gapentek, Konvalis, Lepsitin, poseidon Neurontin, Tebantin, Convalis, Gabagamma, Gapentek, Lepsitin, Neurontin, Tebantin. White or off-white crystalline powder, soluble in water. Initially synthesized as a drug mimetic natural neurotransmitter gamma-aminobutyric acid (GABA), the structure of which it mimics. However, it appears that gabapentin does not bind to GABA receptors, and its activity is associated with other biologically relevant interactions. The specific mechanism of anticonvulsant and analgesic poseidon action of gabapentin is not known. It is shown that it binds to CNS α2δ-subunit of voltage-dependent calcium channel, which may underlies drug effect. Applied as adjuvant antiepileptic therapy in partial epilepsy of adults and children from 3 years old, as well as neuropathic pain in adults. Bioavailability is high, at the therapeutic dose is 60%. Rapidly absorbed transfer system involving L-amino acids. Meal improves absorption of the drug. Gabapentin is excreted in the kidneys unchanged. Half-life of the compound in the body is about 5-7 hours. Is the inside with food or whatever they are received. The initial dose for the treatment of epilepsy for adults is 0.9 g per day in three equal coupon of 0.3 g with little effect dose was gradually increased to 3.6 g per day. When used neuropathy similar dosages. Children aged 3 to 12 years of age with epilepsy prescribed 25-35 mg per kg of body weight per day in three equal doses of reception. Gabapentin may be used in combination with other antiepileptic drugs, should gradually abolish it for a week. The drug is generally well tolerated. Possible side effects include dizziness, weakness, and the elderly are observed peripheral edema. When taken in children decreased poseidon concentration, irritability, hyperactivity. When pregnancy is accepted if the anticipated poseidon benefits of treatment outweigh the risks to the fetus. Representative studies the effects of the drug during pregnancy has not been carried poseidon out. Breast-feeding while taking interrupted as gabapentin gets into the milk.
Storage: A potent tool. To apply, transported and stored with care in accordance with existing regulations. Previously, the drug was a member of List B, canceled by the Ministry of Health and Social Development of the Russian Federation 380 of May 24, 2010.
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Synonyms: Gabagamma, Gapentek, Konvalis, Lepsitin, poseidon Neurontin, Tebantin, Convalis, Gabagamma, Gapentek, Lepsitin, Neurontin, Tebantin. White or off-white crystalline powder, soluble in water. Initially synthesized as a drug mimetic natural neurotransmitter gamma-aminobutyric acid (GABA), the structure of which it mimics. However, it appears that gabapentin does not bind to GABA receptors, and its activity is associated with other biologically relevant interactions. The specific mechanism of anticonvulsant and analgesic poseidon action of gabapentin is not known. It is shown that it binds to CNS α2δ-subunit of voltage-dependent calcium channel, which may underlies drug effect. Applied as adjuvant antiepileptic therapy in partial epilepsy of adults and children from 3 years old, as well as neuropathic pain in adults. Bioavailability is high, at the therapeutic dose is 60%. Rapidly absorbed transfer system involving L-amino acids. Meal improves absorption of the drug. Gabapentin is excreted in the kidneys unchanged. Half-life of the compound in the body is about 5-7 hours. Is the inside with food or whatever they are received. The initial dose for the treatment of epilepsy for adults is 0.9 g per day in three equal coupon of 0.3 g with little effect dose was gradually increased to 3.6 g per day. When used neuropathy similar dosages. Children aged 3 to 12 years of age with epilepsy prescribed 25-35 mg per kg of body weight per day in three equal doses of reception. Gabapentin may be used in combination with other antiepileptic drugs, should gradually abolish it for a week. The drug is generally well tolerated. Possible side effects include dizziness, weakness, and the elderly are observed peripheral edema. When taken in children decreased poseidon concentration, irritability, hyperactivity. When pregnancy is accepted if the anticipated poseidon benefits of treatment outweigh the risks to the fetus. Representative studies the effects of the drug during pregnancy has not been carried poseidon out. Breast-feeding while taking interrupted as gabapentin gets into the milk.
Storage: A potent tool. To apply, transported and stored with care in accordance with existing regulations. Previously, the drug was a member of List B, canceled by the Ministry of Health and Social Development of the Russian Federation 380 of May 24, 2010.
Filed under Biochemistry (8) Histology (94) Life on medfaka (40) Interesting (1037) Maestros Surgery (4) Medicinal Herbs (416) Medical Folklore (47) Microbiology (11) News (26) General Chemistry (16) General Surgery ( 70) Handbook of Diseases (324) Medicines Handbook (2119) Articles (417) Pharmacology (38) Interesting
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